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Inhaled Fluticasone Furoate for Outpatient Treatment of Covid-19

Authors:
David R. Boulware, Christopher J. Lindsell, Thomas G. Stewart, Adrian F. Hernandez, Sean Collins, Matthew William McCarthy, Dushyantha Jayaweera, Nina Gentile, Mario Castro, Mark Sulkowski

Abstract

This randomized, placebo-controlled trial evaluated inhaled fluticasone furoate (200 µg daily for 14 days) in nonhospitalized U.S. adults with mild-to-moderate Covid-19. Among 1277 analyzed participants, there was no significant difference in time to sustained symptom resolution compared to placebo. Hospitalizations were rare and identical across both groups (0.5%). However, urgent care and emergency visits were slightly more frequent in the treatment group. The study concludes that fluticasone furoate did not improve recovery time or clinical outcomes for Covid-19.

Keywords: Covid-19 fluticasone furoate outpatient therapy randomized trial
DOI: https://doi.ms/10.00420/ms/3974/WF96J/NIQ | Volume: 389 | Issue: 12 | Views: 0
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