Cutaneous Leishmaniasis

A previously healthy 3-year-old boy presented with a 6-week history of painless bumps and ulcers on his left leg, following itchy insect bites during his migration from Venezuela. Physical examination revealed ulcerated plaques with rolled borders and satellite papules on the lower leg, buttocks, and back. Histopathological analysis showed severe lymphohistiocytic infiltration, and polymerase-chain-reaction testing identified Leishmania guyanensis, confirming cutaneous leishmaniasis. This case highlights the role of climate change in expanding the geographic range of sandfly vectors, increasing infection risks, particularly among vulnerable populations such as migrants. The patient's lesions resolved after a 28-day course of miltefosine. This report underscores the intersection of environmental change, global migration, and emerging infectious diseases.

A previously healthy 3-year-old boy presented with a 6-week history of painless bumps and ulcers on his left leg, following itchy insect bites during his migration from Venezuela. Physical examination revealed ulcerated plaques with rolled borders and satellite papules on the lower leg, buttocks, and back. Histopathological analysis showed severe lymphohistiocytic infiltration, and polymerase-chain-reaction testing identified Leishmania guyanensis, confirming cutaneous leishmaniasis. This case highlights the role of climate change in expanding the geographic range of sandfly vectors, increasing infection risks, particularly among vulnerable populations such as migrants. The patient's lesions resolved after a 28-day course of miltefosine. This report underscores the intersection of environmental change, global migration, and emerging infectious diseases.