Acute Ocular Toxoplasmosis

   This Images in Clinical Medicine case features a 49-year-old man with a one-week history of blurry vision and glare in his left eye, without systemic symptoms. Ophthalmologic evaluation showed 20/200 vision in the affected eye, granulomatous uveitis, and focal chorioretinitis with vitritis, producing a “headlight in the fog” appearance. The diagnosis was acute ocular toxoplasmosis—recognized as the most common infectious cause of posterior uveitis. Clinical findings and patient history (including pet contact but no exposure to raw meat or other animals) supported the diagnosis. Oral antimicrobial and systemic corticosteroid therapy led to reduced inflammation after one month, though visual acuity remained impaired. The case underscores typical presentation, diagnostic considerations, and treatment response in ocular toxoplasmosis.

   This Images in Clinical Medicine case features a 49-year-old man with a one-week history of blurry vision and glare in his left eye, without systemic symptoms. Ophthalmologic evaluation showed 20/200 vision in the affected eye, granulomatous uveitis, and focal chorioretinitis with vitritis, producing a “headlight in the fog” appearance. The diagnosis was acute ocular toxoplasmosis—recognized as the most common infectious cause of posterior uveitis. Clinical findings and patient history (including pet contact but no exposure to raw meat or other animals) supported the diagnosis. Oral antimicrobial and systemic corticosteroid therapy led to reduced inflammation after one month, though visual acuity remained impaired. The case underscores typical presentation, diagnostic considerations, and treatment response in ocular toxoplasmosis.