Intensive Blood-Pressure Control in Patients with Type 2 Diabetes

This study investigated the effects of intensive versus standard blood pressure control in patients with type 2 diabetes and elevated systolic blood pressure. A total of 12,821 patients were randomly assigned to intensive treatment (targeting systolic blood pressure <120 mm Hg) or standard treatment (targeting <140 mm Hg). Over a median follow up of 4.2 years, the intensive treatment group had a significantly lower incidence of major cardiovascular events (1.65 vs. 2.09 events per 100 person years; hazard ratio, 0.79; 95% CI, 0.69–0.90; P<0.001). However, symptomatic hypotension and hyperkalemia occurred more frequently in the intensive treatment group. The findings support intensive blood pressure control for reducing cardiovascular risk in this population, though careful monitoring for adverse effects is warranted.

This study investigated the effects of intensive versus standard blood pressure control in patients with type 2 diabetes and elevated systolic blood pressure. A total of 12,821 patients were randomly assigned to intensive treatment (targeting systolic blood pressure <120 mm Hg) or standard treatment (targeting <140 mm Hg). Over a median follow up of 4.2 years, the intensive treatment group had a significantly lower incidence of major cardiovascular events (1.65 vs. 2.09 events per 100 person years; hazard ratio, 0.79; 95% CI, 0.69–0.90; P<0.001). However, symptomatic hypotension and hyperkalemia occurred more frequently in the intensive treatment group. The findings support intensive blood pressure control for reducing cardiovascular risk in this population, though careful monitoring for adverse effects is warranted.