Current Management of Glycemia in Children with Type 1 Diabetes Mellitus
Abstract
This clinical practice article reviews evidence based strategies for managing glycemia in children with type 1 diabetes mellitus (T1DM). Key points include:
Tight glycemic control reduces long term complications but requires balancing hypoglycemia risks.
Technological advances: Continuous glucose monitors (CGMs), smart insulin pens, and hybrid closed loop insulin delivery systems improve time in range and quality of life.
Insulin regimens: Basal bolus therapy with rapid/long acting analogs remains standard, though newer formulations (e.g., ultra rapid insulins) and delivery methods (e.g., pumps) offer flexibility.
Emerging therapies: Ready to use glucagon formulations and automated insulin delivery systems address hypoglycemia and hyperglycemia.
Challenges: Disparities in access to technology and high insulin costs persist.
The authors recommend individualized care plans integrating education, technology, and multidisciplinary support.