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Current Management of Glycemia in Children with Type 1 Diabetes Mellitus

Authors:
Mark A. Sperling, Lori M. Laffel

Abstract

This clinical practice article reviews evidence based strategies for managing glycemia in children with type 1 diabetes mellitus (T1DM). Key points include:

  • Tight glycemic control reduces long term complications but requires balancing hypoglycemia risks.

  • Technological advances: Continuous glucose monitors (CGMs), smart insulin pens, and hybrid closed loop insulin delivery systems improve time in range and quality of life.

  • Insulin regimens: Basal bolus therapy with rapid/long acting analogs remains standard, though newer formulations (e.g., ultra rapid insulins) and delivery methods (e.g., pumps) offer flexibility.

  • Emerging therapies: Ready to use glucagon formulations and automated insulin delivery systems address hypoglycemia and hyperglycemia.

  • Challenges: Disparities in access to technology and high insulin costs persist.

The authors recommend individualized care plans integrating education, technology, and multidisciplinary support.

Keywords: Type 1 diabetes mellitus pediatric diabetes glycemic control continuous glucose monitoring (CGM) insulin therapy
DOI: https://doi.ms/10.00420/ms/1697/ZR7KY/ONG | Volume: 386 | Issue: 12 | Views: 0
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