Expression of Concern: Mehra MR et al. Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19

This editorial notice issues an official Expression of Concern regarding a previously published study that examined the relationship between cardiovascular disease, drug therapy particularly ACE inhibitors and ARBs, and mortality in COVID-19 patients. The original article by Mehra et al. was based on a large international database comprising electronic health records from 169 hospitals across three continents. Concerns have since emerged about the integrity and reliability of the data used in the study. The editorial indicates that further evidence has been requested from the authors and advises readers to interpret the original findings with caution. It also references two independently conducted studies that offer alternative analyses

This editorial notice issues an official Expression of Concern regarding a previously published study that examined the relationship between cardiovascular disease, drug therapy particularly ACE inhibitors and ARBs, and mortality in COVID-19 patients. The original article by Mehra et al. was based on a large international database comprising electronic health records from 169 hospitals across three continents. Concerns have since emerged about the integrity and reliability of the data used in the study. The editorial indicates that further evidence has been requested from the authors and advises readers to interpret the original findings with caution. It also references two independently conducted studies that offer alternative analyses