Darier’s Sign in Solitary Mastocytoma
Abstract
A previously healthy 10-month-old girl presented with an intermittently itchy and swollen skin lesion on her neck, which had progressively enlarged over six months. Physical examination revealed a well-demarcated, tan plaque that exhibited Darier’s sign upon firm rubbing. A diagnosis of solitary mastocytoma was made, a localized form of cutaneous mastocytosis characterized by excessive mast cells in the skin. The condition commonly manifests in infancy and tends to resolve spontaneously in childhood. Treatment included topical glucocorticoid ointment and oral diphenhydramine for symptomatic relief. Routine follow-up was deemed unnecessary unless unexpected lesion changes occurred.