Highly innovative drugs in the Czech Republic: retrospective analysis of impact on early market entry, regular reimbursement system entry and public pharmaceutical expenditure

Growing unmet need in treatment of very severe and rare diseases is enhancing a development of new innovative drugs. Consequently, the inclusion of these drugs in the reimbursement system is becoming a critical issue in many countries, as most of them prove their clinical and cost effectiveness just partly at the time of submission

Growing unmet need in treatment of very severe and rare diseases is enhancing a development of new innovative drugs. Consequently, the inclusion of these drugs in the reimbursement system is becoming a critical issue in many countries, as most of them prove their clinical and cost effectiveness just partly at the time of submission