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Neonatal Resuscitation in 22-Week Pregnancies

Authors:
Clement D. Lee, M.D. (Case Vignette); Leif Nelin, M.D. (Option 1); Elizabeth E. Foglia, M.D., M.S.C.E. (Option 2)

Abstract

This interactive clinical decision feature presents opposing expert perspectives on managing neonates born at 22 weeks’ gestation, the current limit of viability. Option 1 (Dr. Nelin) advocates for universal resuscitation, citing improved survival rates (up to 70% in some studies) and reduced disparities through standardized care. Option 2 (Dr. Foglia) supports selective resuscitation, emphasizing high morbidity/mortality (29% survival, 11% without major complications), parental autonomy, and the experimental nature of care at this gestational age. The debate highlights ethical dilemmas, prognostic uncertainties, and institutional variability in outcomes.

Keywords: Neonatal resuscitation extreme prematurity 22-week gestation viability perinatal ethics shared decision-making NICU outcomes neurodevelopmental impairment
DOI: https://doi.ms/10.00420/ms/0609/8ZN8X/CTJ | Volume: 386 | Issue: 4 | Views: 0
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