Direct to Consumer Platforms for New Antiobesity Medications — Concerns and Potential Opportunities

This perspective examines the rise of direct to consumer (DTC) platforms for antiobesity medications like semaglutide and tirzepatide, driven by high demand and barriers in traditional healthcare (e.g., long wait times, cost, insurance hurdles). The authors outline three DTC models integrated weight management programs (e.g., WeightWatchers), wellness centers, and independent online platforms highlighting benefits such as improved access and reduced stigma. However, concerns include risks from unmonitored use (e.g., medication interactions, weight cycling) and regulatory gaps, exemplified by compounded semaglutide formulations. Drawing parallels to DTC testosterone therapy, the authors propose a framework for safe DTC prescribing, emphasizing standardized diagnostics, interdisciplinary coordination, and FDA oversight. They advocate for research on guideline adherence and integration of DTC platforms with traditional care to balance accessibility with patient safety.

This perspective examines the rise of direct to consumer (DTC) platforms for antiobesity medications like semaglutide and tirzepatide, driven by high demand and barriers in traditional healthcare (e.g., long wait times, cost, insurance hurdles). The authors outline three DTC models integrated weight management programs (e.g., WeightWatchers), wellness centers, and independent online platforms highlighting benefits such as improved access and reduced stigma. However, concerns include risks from unmonitored use (e.g., medication interactions, weight cycling) and regulatory gaps, exemplified by compounded semaglutide formulations. Drawing parallels to DTC testosterone therapy, the authors propose a framework for safe DTC prescribing, emphasizing standardized diagnostics, interdisciplinary coordination, and FDA oversight. They advocate for research on guideline adherence and integration of DTC platforms with traditional care to balance accessibility with patient safety.