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Herbal medicines have traditionally been used as an effective digestive medicine. However, compared to the …
Background: Short and long-term sequelae after admission to the intensive care unit (ICU) for coronavirus …
Oridonin, a bioactive diterpenoid isolated from Rabdosia rubescens, has been reported to exert anticancer activity …
Objective: Evaluate the prognostic value of monocyte-lymphocyte ratio (MLR) in patients with stage I endometrial …
The Acute Respiratory Distress Syndrome (ARDS) is common in patients on the Intensive Care Unit …
Background: Implant loosening – either infectious or aseptic- is a still a major complication in …
To investigate the effect of zinc (Zn) supplementation on intestinal microflora changes and bacterial translocation …
RRx-001 is a small molecule NLRP3 inflammasome inhibitor with anti-CD47 and antiangiogenic/vascular normalization properties in …
Obesity associates with macrophage accumulation in adipose tissue where these infiltrating cells interact with adipocytes …
Distinguishing between high-grade and low-grade meningiomas might be difficult but has high clinical value in …
Background: The police force has the mandate to protect citizens and enforce the law for …
: Although vascular risk factors have been found to be closely related to the development …
Rationale: Since non-invasive tests for prediction of liver fibrosis have a poor diagnostic performance for …
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer with a high …
Fine particulate matter (PM2.5) is the critical cause of lung cancer and can further promote …
Octacalcium phosphate (OCP), a type of bioactive ceramics, may be associated with dentine, tooth apatite, …
The interaction between enteral nutrients (ENs) and drugs co-administered through a nasogastric (NG) tube reportedly …
Previous microarray analysis on peripheral blood leukocytes from three patients with acute myocardial infarction (AMI) …
Background: Despite several studies on the effect of adeno-associated virus (AAV)-based therapeutics on osteoarthritis (OA), …
Colorectal cancer (CRC) is a worldwide health problem. Glucose-regulated protein 94 (GRP94) is known as …
The anti-cancer effects of [6]-gingerol ([6]-GIN), the main active polyphenol of ginger (Zingiber officinale), were …
This study aimed to determine the ability of single fiber reflectance (SFR) spectroscopy incorporated in …
Aims: Long noncoding RNAs (lncRNAs) play key roles in the pathophysiology of DKD involving actions …
Introduction: Post-anaesthetic sore throat (PAST) is a well-recognized consequence of tracheal intubation; however, quantitative morphometric …
Osteoarthritis (OA) is a common joint disease characterized by degradation and inflammation of cartilage extracellular …
Background: The purpose of this study was to investigate the effect of general anesthesia on …
As a rare type of gestational trophoblastic disease, placental site trophoblastic tumor (PSTT) is originated …
Objective: To explore a way to reverse the drug resistance for irradiated CNE-1 human nasopharyngeal …
Introduction: Sugammadex has been shown to be associated with prolongation of prothrombin time and activated …
Background: Chronic kidney disease (CKD) is a major risk factor for coronary artery disease and …
Cancer incidence is rapidly growing, and cancer is the leading cause of death worldwide in …
We investigated the potential of gelatin microspheres (GMs) loaded with platelet-rich plasma (PRP) to enhance …
Background: Neutrophil extracellular traps (NETs) have been implicated in host immune responses. Attempts have been …
Four-limb blood pressure measurement could improve mortality prediction in the elderly. However, there was no …
Inflammation-related prostate fibrosis (PF) is strongly associated with impaired urethral function and lower urinary tract …
Aplastic anemia (AA) is a rare disorder characterized by the suppression of bone marrow function …
Background: Multiple myeloma (MM) is the second most common hematological malignancy, which is still incurable …
Background: Chuanxiong Rhizoma is one of the traditional Chinese medicines which have been used for …
Objective: Interleukin-17 (IL-17) C is a cytokine expressed by epithelial cells in response to bacterial …
Letermovir (LMV) is a new antiviral drug used to prevent cytomegalovirus infection in hematopoietic stem …
Purpose: Pancreatic ductal adenocarcinoma (PDAC) with difficulty in early diagnosis does not respond well to …
The azoxymethane (AOM)/dextran sulfate sodium (DSS) murine model is commonly used to study colitis-associated cancer. …
Resistance against tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell death of cancer cells is a …
This study sought to evaluate associations between nephrolithiasis and hemorrhagic and ischemic stroke using a …
The anti-cancer mechanisms of Radix Sophorae Flavescentis were investigated in 5637 bladder cancer cells. Radix …
Purpose: Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly in …
In our previous study, we identified three miRNAs (hsa-miR-421, hsa-miR-29b-1-5p, and hsa-miR-27b-5p) with two mRNAs …
Objectives: The 46,XX disorders of sex development (DSD) is a rare genetic cause of male …
Abnormal angiogenesis is one of the significant features in periodontitis leading to progressive inflammation, but …
Peripheral nerve injury is known to activate the hypoxia-inducible factor-1α (HIF-1α) pathway as one of …
Background: Studies have shown inconsistent results regarding the association between circulating osteoprotegerin (OPG) levels and …
Background: Colorectal cancer (CRC) is the third commonly diagnosed cancer worldwide. Recurrence of CRC (Re) …
Multipotential ability of bone marrow-derived cells has been clarified, and their involvement in repair and …
Introduction: Regenerative capacity of the heart is limited, and the post-infarct left ventricle (LV) dysfunction …
Background: Preterm birth is strongly associated with increasing mortality, incidence of disability, intensity of neonatal …
The aim of this study was to elucidate the role of fibroblasts in bisphosphonate-related osteonecrosis …
Background: Hyperadiponectinemia is an indicator of worse outcomes in advanced heart failure (HF), its role …
There is still a great unmet medical need concerning diagnosis and treatment of breast cancer …
The prevalence of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) is increasing worldwide. …
The purposes of this study were to examine whether there were associations among matrix metalloproteinase-11 …
Background APOBEC3H (A3H) gene presents variation at 2 positions (rs139297 and rs79323350) leading to a …
Background: The efficacy of dexamethasone plus palonosetron for postoperative nausea and vomiting (PONV) prophylaxis is …
Aim: Sulfasalazine (SSZ) displayed anti-cancer activities. Vitamin E succinate (VES) could inhibit cell growth in …
Background: Controlled diagnostic studies have established the prevalence of cervical facet joint pain to range …
Inducible costimulator (ICOS) plays an important role in the suppressive immunity mediated by regulatory T …
Long-chain fatty acids are the most abundant fatty acids and are essential for various physiological …
The objective of this study was to determine the relationship between glucose dosage in parenteral …
Inflammation triggered by the innate immune system is a strategy to protect organisms from the …
Cancer metastasis is a vital trait in malignancies with complicated early diagnosis and therapeutic management. …
A number of biomaterials have been developed, some of which already enjoy widespread clinic use. …
Background: The health benefits of probiotics are well established and known to be strain-specific. However, …
In this article, the significance of anterior segment optical coherence tomography (AS-OCT) to aid the …
The clinical and genetic heterogeneity of Triple Negative Breast Cancer (TNBC) and the lack of …
Aims: GS28 (Golgi SNARE protein, 28 kDa), a member of the soluble N-ethylmaleimide-sensitive factor attachment …
Purpose: To investigate whether lacrimal canaliculus epithelial stem cells (LCESC) could be isolated and expanded …
The purpose of the role of antioxidant enzymes and mitochondria in the developmental mechanism of …
There is a great interest in searching for diagnostic biomarkers in prostate cancer patients. The …
Background: Electrolytically-generated acid functional water (FW) is obtained by electrolyzing low concentrations of saline. Although …
Background: The aim of this prospective study was to investigate the influence of long-term physical …
Objectives: To survey time-related shifts in number of suicide-related events (SRE) during smoking cessation treatment …
Background: Postoperative immune suppression, particularly a loss of cell-mediated immunity, is commonly seen after surgery …
Background: To examine the influence of the severity of portal hemodynamic abnormality on the prognosis …
Objectives: To determine whether the soluble programmed cell death ligand 1 (sPD-L1) levels in patients …
Introduction: This study addresses minimally invasive anesthesiologic and analgetic approaches for stone surgery in the …
Hypertension is a severe threat to human being’s health due to its association with many …
Background. Total laparoscopic hysterectomy (TLH) causes various types of postoperative pain, and the pain pattern …
Atherosclerosis origins early in childhood. Aim of the study was to investigate vascular signature and …
Background: Although the use of corticosteroids has been linked to high incidence of weight gain, …
Objectives and Background: Atrial fibrillation (AF) is associated with clinical deterioration, stroke and disability in …
Recent studies have demonstrated that inflammatory cells are a component that plays a role in …
Tumor necrosis factor-α (TNF-α) inhibitors are increasingly being used as treatment for rheumatoid arthritis (RA). …
Background: Syndecan-1 (SDC1) is reported to modulate several key processes of tumorigenesis and has variable …
Background: Early assessment and aggressive hemodynamic treatment have been shown to increase the survival of …
OBJECTIVES: Increasing evidence suggests that vitamin D plays a role in the development of chronic …
We aimed to investigate the potential mediators and relationship affecting congenital exercise performance in an …
Objectives: Diabetic cardiomyopathy (DCM) is an established complication of diabetes mellitus. In West Virginia, the …
Background: Vascular calcification (VC) is a key process associated with cardiovascular mortality in dialysis patients. …
The differentiation of mesenchymal stem cells towards an osteoblastic fate depends on numerous signaling pathways, …
Lyme disease has emerged as a major health concern in Canada, where the etiological agent, …
Background: Pain plays roles in both the nervous system and immune system. Changes in the …
Recent advances in diagnostic technologies have revealed that nonsteroidal anti-inflammatory drugs (NSAIDs) can cause serious …
Dehydroepiandrosterone (DHEA), the most abundant sex steroid, is primarily secreted by the adrenal gland and …
We carried out an experiment to induce traumatic occlusion in mice periodontal tissue and analyzed …
Abstract Introduction: An increased production of oxidizing species related to reactive oral diseases, such as …
Aims: Phrenic nerve palsy (PNP) is still a cause for concern in Cryoballoon ablation (CBA) …
Background: Atypical squamous cell cannot exclude high-grade squamous intraepithelial lesion (ASC-H) and low-grade intraepithelial lesion …
Background: Non-steroidal anti-inflammatory drugs induce the serious side effect of small intestinal ulcerations (SIUs), but …
The expression of Notch in 30 cases of pleomorphic adenoma was examined by immunohistochemistry. Comparing …
Background: Microglia are involved in immune surveillance in intact brains and become activated in response …
BACKGROUND: Collagen Triple Helix Repeat Containing 1 (CTHRC1) is a protein often found to be …
Background and aims: The etiopathogenesis of inflammatory bowel diseases (IBD) remains largely unexplained. Flotillins (flotillin-1 …
The healing process of the skin is a dynamic procedure mediated through a complex feedback …
Background: The use of a retroflexed view exposes the entire tumor surface, which is obscured …
Background: Compliance index derived from digital volume pulse (CI-DVP), measuring the relationship between volume and …
Aim: To evaluate the effect of antenatal corticosteroids (ANS) on short- and long-term outcomes in …
Autoimmune hepatitis (AIH) can arise de novo after liver transplantation (LT) for non-autoimmune liver diseases. …
Study Design: Comparative assessment of randomized controlled trials of caudal and lumbar interlaminar epidural injections …
Background: Opioid induced bowel dysfunction is the most common side effect of preoperatively administrated morphine, …
Background: Vascular endothelial growth factor (VEGF) is essential for normal vascular growth and development during …
Background: Our purpose was to provide the clinical advantages of the laparoscopic approach compare to …
Objective: Peritoneal adhesions following surgery are a common, serious pathology with severe complications. Appropriate animal …
Objectives Oxycodone is semi-synthetic opioid, oral and parenteral preparations have been widely used for acute …
In this prospective, randomized, double-blind, trial conducted in two parts, we examined the effects of …
A Human Head Surrogate has been developed for use in behind helmet blunt trauma experiments. …
Background: Adiponectin is an anti-inflammatory and cardio-protective cytokine. However, several studies have demonstrated that plasma …
Background: Our previous studies of human breast and prostate cancer have shown that aberrant immune …
Study Design: A randomized, double-blind, active-controlled trial. Objective: To assess the effectiveness of cervical interlaminar …
Background. Although researchers have consistently demonstrated systemic inflammation in chronic obstructive pulmonary disease (COPD), its …
Background: Blood stream infections caused by Bacillus cereus or Serratia marcescens in patients receiving peripheral …
Objective: As a main cellular component within the disc, nucleus pulposus (NP) cells play important …
Background: Anti-angiogenesis is a promising therapeutic strategy for locally advanced breast cancer. We performed this …
Keloid is characterized by fibroblastic cell proliferation and abundant collagen synthesis. Numerous studies have shown …
Background: Areca nut chewing is associated with the risk of obesity, metabolic syndrome, hypertension, and …
Purpose: The purpose of the present study was to investigate the possible role of Ki-67 …
To evaluate the feasibility of cell transplantation to treat bradyarrhythmia, we analyzed the in vivo …
Objectives; Pulmonary hypertension (PH) is a common and well established complication of chronic obstructive pulmonary …
Background: Reports have been accumulating that genetic properties are predictive of clinical response after and/or …
Nucleos(t)ide analogues (NAs) lead to viral suppression and undetectable hepatitis B virus (HBV) DNA in …
Objective: In this study, we investigated the predictive capacity of the brachial–ankle aortic pulse wave …
The correlation of coronary artery disease (CAD) with pro-oxidant/antioxidant balance and oxidative DNA damage was …
Background: Metabolic syndrome (Mets) is reportedly associated with chronic obstructive pulmonary disease (COPD). However, the …
Objective: Although the anterior approach is normally used for elective laparoscopic splenectomy (LS), the posterolateral …
Objective: To investigate the impact of antithyroid antibody on pregnancy outcome following the in vitro …
Purpose: To compare umbilical arterial gas parameters in the second twin of twin pregnancies according …
Background: The US Surgeon General’s Report on Bone Health suggests America’s bone-health is in jeopardy …
Background: The purpose of this research is to discover whether measurement of cervical length and …
This study aimed to retrospectively summarize the clinical signs, diagnosis, and treatment of congenital bronchial …
Objective: Case reports showing that proton-pump inhibitors (PPIs), omeprazole and esomeprazole, can cause hypomagnesaemia have …
Objective: To investigate whether emulsified isoflurane preconditioning could reduce lung injury induced by hepatic I/R …
Progress in genomics and proteomics attended to the door for better understanding the recent rapid …
Introduction: Not all convulsive episodes are due to epilepsy and a number of these have …
Objective: We assessed the ability of two commercially-available fractions labeled SX and D derived from …
Being overweight or obese is associated with an increased risk for the development of non-insulin-dependent …
Nucleophosmin (NPM1) is an abundant and ubiquitously expressed phosphoprotein that is known to influence solid …
Background: Chronic pulmonary disorders, such as chronic obstructive pulmonary disease (COPD) and fibrosing lung diseases, …
Refractory intracranial hypertension is a leading cause of poor neurological outcomes in patients with severe …
Background: To identify the microorganisms that can grow rapidly in total parenteral nutrition (TPN) solutions, …
Age-associated thymic involution is characterized by decreased thymopoiesis, adipocyte deposition and changes in the expression …
Study Design: Prospective observational study. Objective: Our aim is to investigate the efficacy and safety …
The value of bronchoalveolar lavage (BAL) still remains controversial, prompting a need for further improvement. …
Infections still remain one of the most devastating complications in hip joint surgery. Classification of …
The aim of this paper is to report new options in the treatment of lymphedema …
Parvovirus B19 is a widespread virus with diverse clinical presentations. The viral nonstructural protein, NS1, …
Psoriasis is associated with an increased risk of cardiovascular disease, a hallmark of which is …
Papers of this special issue are based on the presentations given in the Congress “Eye …
The pathogenesis of neurological diseases and disorders remains mostly unknown. Neuroinflammation has been proposed as …
We study the osteoinductive effect of the hyaluronic acid (HA) by using an esterified low-molecular …
Human Toll-like receptors (TLRs) comprise a family of proteins that recognizes pathogen-associated molecular patterns (PAMPs) …
The treatment of condylar process fractures has generated a great deal of discussion and controversy …
Background: Accurate, non-invasive diagnosis of, and screening for, coronary artery disease (CAD) and restenosis after …
Because the prevalence of obesity has increased dramatically in recent years, one of the key …
Introduction: Some forms of tinnitus are considered to be auditory phantom phenomena related to reorganization …
Various single nucleotide polymorphisms (SNPs) have explained the association between Helicobacter pylori (H. pylori) and …
Hepatic steatosis is a common presentation in HCV-infected individuals. Drs. Yoon and Hu review the …
The epidermal growth factor receptor (EGFR) is overexpressed in the majority of non-small cell lung …
The importance of evidence for every branch of medicine in teaching in order to orient …
Various DNA alterations can be caused by exposure to environmental and endogenous carcinogens. Most of …
Micro RNAs (miRNAs) are 19-24 nucleotide long non-coding RNAs that posttranscriptionally modulate gene expression. They …
Cyclophosphamide (CY) is a cytostatic agent that produces systemic toxicity especially on cells with high …
We investigated changes in the geography of Chronic Obstructuve Pulmonary Disease (COPD) hospitalization charges in …
We examined the expression of the sodium-dependent glucose co-transporter system (hSGLT3) in skeletal muscle of …
The Event-Related Potential (ERP) is a time-locked measure of electrical activity of the cerebral surface …
Birth defects – or by according to the World Health Organization’s (WHO) term: congenital anomalies …
Osteoporosis is characterized by decreased bone mineral density and mechanistic imbalances of bone tissue that …
Background & Aims: At least 500 µg of folic acid are required daily to treat …
Topics in this issue touch important progresses of current HBV study. Authors have provided their …
The theoretical possibility of applying gene transfer methodologies to the human germline is explored. Transgenic …
Severe acute respiratory syndrome (SARS) is frequently complicated with acute respiratory failure. In this article, …
Severe acute respiratory syndrome (SARS) is frequently complicated with acute respiratory failure. In this article, …
