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A 38-year-old man presented with a 9-month history of mildly itchy groin rash misdiagnosed as …
This editorial reviews the Protect trial, a cluster-randomized study evaluating universal decolonization in 28 California …
This editorial discusses the persistent global challenge of meningococcal disease, emphasizing its epidemic impact in …
This Perspective analyzes the contentious debate surrounding SARS-CoV-2's origins, outlining both the zoonotic spillover hypothesis …
This Perspective article discusses the ethical, legal, and clinical implications of approving workplace accommodations …
A 43-year-old man, originally from northern South America and living in Panama, underwent evaluation at …
The CREDENCE trial investigated the efficacy of canagliflozin, an SGLT2 inhibitor, in patients with type …
A 47-year-old man presented with a chronic, painful scalp rash unresponsive to antibiotics. Examination …
This editorial summarizes an audio interview conducted on March 27, 2023, featuring editors of The …
This correspondence reports findings from a study assessing neutralizing antibody and T-cell responses following administration …
This correspondence reanalyzes data from a randomized trial comparing subcutaneous versus intradermal administration of the …
This editorial examines the debate around continuous antibiotic prophylaxis for preventing urinary tract infections (UTIs) …
This multinational, prospective study investigated whether SARS-CoV-2 infection increased the risk of developing islet autoimmunity …
A 58-year-old woman was evaluated at Massachusetts General Hospital for fatigue, abdominal bloating, and eosinophilia …
This editorial highlights a conversation between NEJM editors and Dr. Anthony Fauci, recorded on …
This editorial discusses two randomized controlled trials (PERL and CKD-FIX) investigating the efficacy of urate-lowering …
This Images in Clinical Medicine case features a 49-year-old man with a one-week history …
This paper investigates the meaning of convenience in the development of smart home technologies (SHT), …
This correspondence in The New England Journal of Medicine documents cases of multisystem inflammatory syndrome …
This Original Article from a multicountry, phase 3, double-blind, placebo-controlled trial (MATISSE Study Group) evaluated …
This original research identifies a previously unknown X-linked inborn error of immunity caused by rare …
This phase 3, double-blind, randomized, noninferiority trial compared a new pentavalent meningococcal conjugate vaccine (NmCV-5) …
This Correspondence reports a novel anti–platelet factor 4 (PF4) disorder resembling vaccine-induced immune thrombotic thrombocytopenia …
This perspective critiques the U.S. Supreme Court’s 2025 decision in United States v. Skrmetti, which upheld …
This international randomized platform trial (REMAP-CAP) evaluated simvastatin (80 mg daily) in critically ill Covid-19 …
This instructional summary outlines the principles, equipment, and procedural steps for two surgical hand preparation …
This editorial examines recent progress in preventing leprosy through postexposure prophylaxis. While WHO-endorsed single-dose rifampin …
