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This perspective argues for a shift away from traditional race-based models of health toward frameworks …
This editorial evaluates the Diuretic Comparison Project (DCP)—a pragmatic, randomized trial comparing chlorthalidone and hydrochlorothiazide …
This multimedia instructional article explains how focused cardiac ultrasonography (FCU) can be used at the …
This editorial explores an innovative experimental approach to post-mortem tissue revival and its implications for …
This editorial explores the clinical implications of the TTM and TTM2 trials evaluating targeted temperature …
This observational study analyzed the incidence and clinical outcomes of myocarditis in adolescents (ages 12–15) …
This editorial discusses the findings of the CLOuD trial, which investigated whether hybrid closed loop …
This phase 1 dose-escalation trial assessed the safety, pharmacodynamics, and efficacy of olpasiran, a small …
This phase 2 trial evaluated the efficacy and safety of baxdrostat, a selective aldosterone synthase …
This multicenter, randomized, placebo-controlled trial (STRESS) evaluated the prophylactic use of methylprednisolone in infants (<1 …
This editorial interprets findings from the BEST-CLI trial, which compared surgical and endovascular revascularization in …
This phase 3 randomized trial (SOLOIST-WHF) evaluated sotagliflozin, a dual SGLT1/SGLT2 inhibitor in patients with …
This editorial evaluates the STOP-ACEi randomized controlled trial, which assessed the clinical impact of continuing …
This Clinical Problem-Solving article details the diagnostic journey of a 50-year-old woman presenting with chest …
Posterior reversible encephalopathy syndrome (PRES) is an acute or subacute neurologic condition characterized by headache, …
This article examines the precarious constitutional right to health care for incarcerated individuals in the …
This study describes two novel homozygous leptin variants (P64S and G59S) identified in unrelated children …
This article discusses the persistent high costs of insulin in the United States and evaluates …
This editorial discusses the findings of a study by Chen et al. (2023) involving 315 …
This multicenter, open-label randomized controlled trial (STOP ACEi) investigated whether discontinuing renin–angiotensin system (RAS) inhibitors—ACE …
This pragmatic trial evaluated the effectiveness of an electronic health record (EHR) based algorithm combined …
This study pooled individual level data from 112 cohort studies across 34 countries (1,518,028 participants; …
This correspondence reports the successful use of RZ358, a novel human anti insulin receptor monoclonal …
This GRADE trial analysis compared microvascular and cardiovascular outcomes across four glucose-lowering agents: glargine, glimepiride, …
A 49-year-old woman with a history of Graves’ disease presented with violaceous, nonpitting, indurated nodules …
This editorial discusses the challenges and progress in pharmacotherapy for nonalcoholic steatohepatitis (NASH), focusing on …
Closed loop control systems of insulin delivery may improve glycemic outcomes in young children with …