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This interactive case discussion evaluates whether empirical antibiotics or chest radiography should guide treatment for …
This open-label, multicenter trial in Kenya evaluated switching HIV patients from a ritonavir-boosted protease inhibitor …
This brief report describes a 58 year old woman with severe ankylosing spondylitis and consanguineous …
This case profiles a 56-year-old woman with end-stage liver disease secondary to metabolic dysfunction-associated steatohepatitis, …
A 24-year-old man was admitted in March 1923 with acute fever, pleuritic chest pain, chills, …
This multicenter, observational, noninferiority study evaluated the safety of kidney transplantation from deceased donors with …
This article discusses innovative approaches to overcoming the challenges of oral delivery for macromolecular drugs, …
This clinical decision article explores the debate over intravenous fluid choice for resuscitation in diabetic …
This essay honors the 2024 Lasker-Bloomberg Public Service Award recipients, Drs. Quarraisha and Salim Abdool …
In June 2019, a tick-bitten patient in Inner Mongolia presented with fever and multiorgan dysfunction, …
This editorial summarizes an NEJM audio interview recorded on February 6, 2023, featuring Drs. Eric …
This randomized, open-label study evaluated the effectiveness of doxycycline postexposure prophylaxis (DoxyPEP) in reducing bacterial …
This 6 month randomized, multicenter trial evaluated the efficacy and safety of a closed loop …
This editorial summarizes an NEJM audio interview recorded on January 30, 2023, with Drs. Eric …
This comprehensive review redefines cryoglobulinemia as two distinct clinical entities: type I, a hyperviscosity-driven vasculopathy …
This phase 2–3 double-blind, placebo-controlled trial evaluated the efficacy and safety of oral nirmatrelvir–ritonavir as …
This correspondence describes a stillbirth associated with vertical transmission of Oropouche virus (OROV) in a …
This firsthand account documents the clinical and ethical decision-making of a critical care physician during …
This article traces the decades-long evolution of vaccine development for respiratory syncytial virus (RSV), highlighting …
A 26-year-old man presented with a 2-month history of a painless, reddish growth on the …
This editorial summarizes an audio interview with NEJM editors discussing prospects for emerging Covid-19 treatments. …
This editorial discusses the TRUNCATE-TB trial, which tested a strategic approach to shortening treatment …
This original article presents results from two phase 2a randomized controlled trials evaluating the safety …
This phase 3 noninferiority trial compares the oral antiviral VV116 to nirmatrelvir–ritonavir in symptomatic adults …
A healthy 2-year-old presented with a 4-week history of painless alopecia and black dots on …
This review examines the profound global health impacts of food and nutrition insecurity, affecting 2.33 …
This editorial discusses the advancements in automated insulin delivery systems for patients with type 1 …
