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This editorial reviews pivotal progress in RSV vaccine development, culminating in 2023 with approval of …
This NEJM editorial by Moskowitz and Gong reviews the implications of the REMAP-CAP trial simvastatin …
This multicenter, double-blind, placebo-controlled trial assessed the efficacy of adding vancomycin to cefazolin prophylaxis in …
This correspondence reports a case of advanced papillary thyroid cancer with lung metastases, where the …
This perspective article outlines the goals of Project NextGen, a $5 billion U.S. government initiative …
This review article explores the diverse mechanisms by which medications can adversely affect thyroid function …
Hypoparathyroidism is a rare disorder characterized by deficient parathyroid hormone (PTH) production, leading to hypocalcemia …
The ACT HIV trial was a double-blind, randomized, placebo-controlled study evaluating adjunctive dexamethasone in 520 …
This letter from the NYC OSMI study reports immunogenicity outcomes following MVA-BN (JYNNEOS) mpox vaccination …
This NEJM Perspective outlines emerging threats to malaria control in sub-Saharan Africa, particularly artemisinin-resistant Plasmodium …
This phase 2 study evaluated the safety and efficacy of vosoritide, a C-type natriuretic peptide …
This case describes a 70-year-old woman from KwaZulu-Natal, South Africa with advanced HIV infection (CD4 …
This perspective piece explores the historical and cultural influence of gender norms on mask-wearing behavior …
This perspective details a multidisciplinary response to a Rift Valley fever (RVF) outbreak in Uganda, …
This editorial reviews advances in understanding and treating cardiac amyloidosis, particularly transthyretin (ATTR) amyloidosis and …
This editorial critiques the findings of the D2d trial, which investigated whether high dose vitamin …
This article explores the role of irisin, a myokine derived from the protein FNDC5, in …
This editorial evaluates the efficacy of prenatal vitamin D supplementation in preventing childhood asthma, focusing …
This randomized, double blind, placebo controlled trial evaluated the efficacy and safety of liraglutide in …
This randomized, placebo controlled trial investigated the effects of marine n–3 (omega 3) fatty acid …
This NEJM Case Records report chronicles a diagnostic challenge involving a 38-year-old woman with progressive …
This correspondence reports the case of a 54 year old man with an inoperable metastatic …
This perspective article highlights the elevated rates of vaccine-preventable infectious diseases in U.S. migrant detention …
A 62-year-old woman presented with recurrent hemorrhagic pericardial effusion and symptoms of early tamponade. Her …
This editorial inaugurates NEJM’s new series on medical ethics, highlighting how advances in medicine continually …
This brief report describes the first clinical case of a gene edited porcine kidney xenotransplant …
The PARTNER 3 trial randomized 1000 patients with severe, symptomatic aortic stenosis and low surgical …