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his editorial discusses a head to head trial comparing tirzepatide and semaglutide for obesity treatment, …
This NEJM review evaluates the prevention of central line–associated bloodstream infections (CLABSIs), which occur from …
This perspective article examines the implications of Idaho’s Fairness in Women’s Sports Act, which bars transgender …
This 15-year follow up study of the Veterans Affairs Diabetes Trial (VADT) evaluated the long-term …
Tirzepatide, a dual GIP and GLP-1 receptor agonist, was compared with semaglutide, a GLP-1 receptor …
This correspondence describes a multidisciplinary approach to oocyte cryopreservation in a 16-year-old transgender male adolescent …
The MULTISTARS AMI trial randomized 840 hemodynamically stable patients with ST-segment elevation myocardial infarction (STEMI) …
This multicenter, double-blind, randomized RESCUE BT2 trial evaluated intravenous tirofiban versus oral aspirin in 1177 …
This perspective examines the health risks of ultraprocessed foods (UPF), defined by the Nova classification …
This NEJM editorial reviews the evolving management of aortic-valve stenosis, emphasizing two key decisions: when …
The DAPA HF trial evaluated the efficacy and safety of dapagliflozin, an SGLT2 inhibitor, in …
This phase 3 trial evaluated the efficacy and safety of once-weekly subcutaneous semaglutide (2.4 mg) …
This case involves a 29-year-old man with sickle cell disease admitted for new, atypical right …
This phase 2, randomized, placebo controlled trial evaluated the efficacy and safety of oveporexton (TAK-861), …
This case report describes a 17 year old male with STAT1 gai of function disease, …
Higher serum urate levels are associated with an increased risk of diabetic kidney disease. This …
This NEJM editorial by Kiran K. Khush discusses the pivotal multicenter trial by Dhar et …
The ILUMIEN IV trial randomized 2487 high-risk patients undergoing PCI those with medication-treated diabetes or …
This NEJM correspondence details a case of a young woman with chronic autoimmune anti–platelet factor …
This comprehensive NEJM review describes the anatomy, pathophysiology, diagnosis, and treatment of right ventricular (RV) …
This phase 2, randomized, placebo controlled trial investigated the efficacy of teplizumab, an anti CD3 …
This study compared the five year outcomes of Roux-en-Y gastric bypass surgery in adolescents and …
This NEJM editorial critiques the ECLS-SHOCK trial, which evaluated whether early use of extracorporeal life …
This editorial contextualizes the NOAH-AFNET 6 trial, which evaluated oral anticoagulation with edoxaban in patients …
This editorial reflects on a decade of genomic screening through the lens of ACMG Secondary …
The OCTOBER trial, conducted across 38 European centers randomized 1201 patients with complex coronary-artery bifurcation …
This editorial discusses the global rise in overweight and obesity, focusing on China, where the …