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This multicenter, randomized, controlled trial evaluated the efficacy and safety of automated insulin delivery (AID) …
This prospective, multicenter randomized trial (RENOVATE-COMPLEX-PCI) compared intravascular imaging–guided versus angiography-guided percutaneous coronary intervention …
A newborn girl presented with a large neck mass detected prenatally at 34 weeks of …
This Science Behind the Study editorial explores the rationale for targeting aldosterone synthesis in resistant …
This article reviews the benefits and risks of hormone therapy for postmenopausal women, focusing on …
Obesity is a chronic disease with limited treatment options in pediatric patients. This randomized, double …
This study analyzed the lifetime risk of cardiovascular disease (CVD) and death from any cause …
This image-based case report presents a 60-year-old man with exertional dyspnea and a history of …
This article explores the challenges and recent advances in beta cell replacement therapy for type …
This double-blind, phase 3 trial (STELLAR) evaluated sotatercept, a ligand trap targeting activins and growth …
This randomized, double-blind, placebo-controlled trial (EMPA-KIDNEY) evaluated empagliflozin in 6609 patients with chronic kidney disease …
In this phase 2b, randomized, placebo controlled trial, the efficacy and safety of efruxifermin, a …
This editorial discusses the clinical, ethical, and logistical considerations surrounding heart transplantation from donors after …
This editorial summarizes findings from the Vitamin D and Omega 3 Trial (VITAL) and its …
This case report describes a 50-year-old man with a history of mitral-valve prolapse and remote …
The DAPA CKD trial evaluated the efficacy and safety of dapagliflozin, an SGLT2 inhibitor, in …
This editorial evaluates cardiovascular disease (CVD) risk among people living with HIV, who face …
This editorial introduces transcatheter arterialization of deep veins, a novel approach for patients with no …
This editorial discusses the emerging role of bempedoic acid, a liver-specific ATP citrate lyase inhibitor …
This randomized, controlled trial (TAME) investigated whether mild hypercapnia (PaCO₂ 50–55 mm Hg) improves neurologic …
This phase 1 multicenter trial evaluated zilebesiran, a hepatocyte-targeted small interfering RNA (siRNA) therapeutic designed …
This multicenter, randomized, placebo-controlled phase 2 trial (BrigHTN) investigated the efficacy and safety of baxdrostat, …
A 25 year old man presented with sudden onset limb weakness, palpitations, and insomnia. Examination …
This clinical decision article discusses the management of an incidentally discovered retrievable inferior vena cava …
This multicenter, randomized noninferiority trial (BeNeDuctus) compared expectant management versus early ibuprofen treatment in 273 …
This clinical decision article explores the management of a 31-year-old woman with type 1 diabetes …
This study describes two cases of acquired parathyroid hormone (PTH) resistance due to autoantibodies targeting …
