Search Everything

Find articles, journals, projects, researchers, and more

Showing 27 of 3429 articles

Golimumab and Beta-Cell Function in Youth with New-Onset Type 1 …

This phase 2 trial evaluated the efficacy of golimumab, a TNF-α inhibitor, in preserving beta  …

DOI: https://doi.ms/10.00420/ms/1081/EOUV1/CIA

Heart Failure with Preserved Ejection Fraction — A Metabolic Disease?

This NEJM editorial explores whether heart failure with preserved ejection fraction (HFpEF) is primarily a …

DOI: https://doi.ms/10.00420/ms/5978/BLFVK/TYA

Interchangeable Insulins — New Pathways for Safe, Effective, Affordable Diabetes …

This perspective discusses the FDA’s draft guidance to streamline the approval of biosimilar insulin products …

DOI: https://doi.ms/10.00420/ms/5381/SUC2R/KSI

Thrombus in Transit across a Patent Foramen Ovale

: This case report describes a 67-year-old woman with atrial fibrillation who was admitted for …

DOI: https://doi.ms/10.00420/ms/0659/JO99S/RZC

Inebilizumab for Treatment of IgG4-Related Disease

This phase 3, double blind, randomized trial evaluated the efficacy and safety of inebilizumab, a …

DOI: https://doi.ms/10.00420/ms/5452/HDGPI/FFG

Effect of Finerenone on Chronic Kidney Disease Outcomes in Type …

Finerenone, a nonsteroidal, selective mineralocorticoid receptor antagonist, was evaluated in patients with chronic kidney disease …

DOI: https://doi.ms/10.00420/ms/8997/UOGDQ/ZSD

Ferric Carboxymaltose in Heart Failure with Iron Deficiency

The HEART-FID trial was a randomized, double-blind study evaluating intravenous ferric carboxymaltose (FCM) versus placebo …

DOI: https://doi.ms/10.00420/ms/1777/NARMT/NEQ

Corin and Left Atrial Cardiomyopathy, Hypertension, Arrhythmia, and Fibrosis

This NEJM brief report describes two Filipino siblings with cardiomyopathy, hypertension, arrhythmia, and isolated left …

DOI: https://doi.ms/10.00420/ms/3922/NMCH9/OXC

Redefining End Points in MASH Cirrhosis

This editorial discusses the challenges of defining clinical trial endpoints for metabolic dysfunction-associated steatohepatitis (MASH) …

DOI: https://doi.ms/10.00420/ms/2721/NM29A/DHR

Constrictive Pericarditis

A 69-year-old woman with a 3-year history of exertional dyspnea presented with signs of volume …

DOI: https://doi.ms/10.00420/ms/0912/45VXN/QMI

Inclisiran for the Treatment of Heterozygous Familial Hypercholesterolemia

This phase 3, double blind, randomized trial evaluated the efficacy and safety of inclisiran, a …

DOI: https://doi.ms/10.00420/ms/5867/N2DF2/BXK

Adenovirus-Associated Thrombocytopenia, Thrombosis, and VITT-like Antibodies

This correspondence describes two patients, a 5-year-old boy and a 58-year-old woman who developed symptomatic …

DOI: https://doi.ms/10.00420/ms/5570/W6S0B/EZY

Effects of Diet versus Gastric Bypass on Metabolic Function in …

This study compared the metabolic effects of Roux-en-Y gastric bypass surgery and diet therapy in …

DOI: https://doi.ms/10.00420/ms/2644/3F7DI/GME

Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 …

This randomized trial evaluated the efficacy and safety of combining finerenone (a nonsteroidal mineralocorticoid receptor …

DOI: https://doi.ms/10.00420/ms/1292/T4IYR/FOK

Pericardial Decompression Syndrome

This case report describes a 14-year-old boy who developed acute hypotension and right ventricular failure …

DOI: https://doi.ms/10.00420/ms/9852/RFI72/GXY

Complete Revascularization in Older Patients with Myocardial Infarction

This editorial evaluates the FIRE trial, which randomized 1445 patients (≥75 years old; median age …

DOI: https://doi.ms/10.00420/ms/6389/0EKYB/YSY

Cardiovascular Outcomes with Ertugliflozin in Type 2 Diabetes

This multicenter, double blind trial evaluated the cardiovascular effects of ertugliflozin, an SGLT2 inhibitor, in …

DOI: https://doi.ms/10.00420/ms/8479/AGIK8/MBC

Catheter Ablation in End-Stage Heart Failure with Atrial Fibrillation

The CASTLE-HTx trial evaluated catheter ablation plus medical therapy versus medical therapy alone in patients …

DOI: https://doi.ms/10.00420/ms/3155/J4OGP/TLM

Optical Coherence Tomography and Eye Care

This NEJM editorial chronicles the invention, engineering foundation, and transformative clinical impact of optical coherence …

DOI: https://doi.ms/10.00420/ms/2575/0EZ9J/PVJ

Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes

This multicenter, double-blind, randomized NOAH-AFNET 6 trial evaluated whether oral anticoagulation with edoxaban benefits patients …

DOI: https://doi.ms/10.00420/ms/6857/4S7BS/QDL

Case 23-2023: A 21-Year-Old Man with Progressive Dyspnea

A 21-year-old college student presented with progressive dyspnea, initially misdiagnosed as exercise-induced asthma. Diagnostic imaging …

DOI: https://doi.ms/10.00420/ms/3883/QEIEK/XXL

Oral Semaglutide and Cardiovascular Outcomes in High-Risk Type 2 Diabetes

This double blind, placebo controlled trial evaluated the cardiovascular efficacy of once daily oral semaglutide …

DOI: https://doi.ms/10.00420/ms/5671/RD8SX/EGH

Finerenone — Halting Relative Hyperaldosteronism in Chronic Kidney Disease

This editorial discusses the role of finerenone, a nonsteroidal mineralocorticoid receptor antagonist, in managing chronic …

DOI: https://doi.ms/10.00420/ms/7409/3CX0X/GJR

Chemical Complexity of Food and Implications for Therapeutics

Poor nutrition is a leading cause of preventable diseases, contributing to over half a million …

DOI: https://doi.ms/10.00420/ms/7365/WEUWL/CPO

Actionable Genotypes and Their Association with Life Span in Iceland

This large-scale population study assessed the prevalence and survival implications of actionable genotypes in 73 …

DOI: https://doi.ms/10.00420/ms/0338/MRB7G/FDC

Hidden in Plain Sight — Reconsidering the Use of Race …

A 70 year old man with a history of hairy cell leukemia (in remission) and …

DOI: https://doi.ms/10.00420/ms/8135/D7F4A/VYM

Addressing Disparities in the Management of Obesity in Primary Care …

This editorial highlights the disparities in obesity management in primary care, particularly among socioeconomically disadvantaged …

DOI: https://doi.ms/10.00420/ms/7708/KHX4V/SRR
Showing 433459 of 3429 articles