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This phase 2 trial evaluated the efficacy of golimumab, a TNF-α inhibitor, in preserving beta …
This NEJM editorial explores whether heart failure with preserved ejection fraction (HFpEF) is primarily a …
This perspective discusses the FDA’s draft guidance to streamline the approval of biosimilar insulin products …
: This case report describes a 67-year-old woman with atrial fibrillation who was admitted for …
This phase 3, double blind, randomized trial evaluated the efficacy and safety of inebilizumab, a …
Finerenone, a nonsteroidal, selective mineralocorticoid receptor antagonist, was evaluated in patients with chronic kidney disease …
The HEART-FID trial was a randomized, double-blind study evaluating intravenous ferric carboxymaltose (FCM) versus placebo …
This NEJM brief report describes two Filipino siblings with cardiomyopathy, hypertension, arrhythmia, and isolated left …
This editorial discusses the challenges of defining clinical trial endpoints for metabolic dysfunction-associated steatohepatitis (MASH) …
A 69-year-old woman with a 3-year history of exertional dyspnea presented with signs of volume …
This phase 3, double blind, randomized trial evaluated the efficacy and safety of inclisiran, a …
This correspondence describes two patients, a 5-year-old boy and a 58-year-old woman who developed symptomatic …
This study compared the metabolic effects of Roux-en-Y gastric bypass surgery and diet therapy in …
This randomized trial evaluated the efficacy and safety of combining finerenone (a nonsteroidal mineralocorticoid receptor …
This case report describes a 14-year-old boy who developed acute hypotension and right ventricular failure …
This editorial evaluates the FIRE trial, which randomized 1445 patients (≥75 years old; median age …
This multicenter, double blind trial evaluated the cardiovascular effects of ertugliflozin, an SGLT2 inhibitor, in …
The CASTLE-HTx trial evaluated catheter ablation plus medical therapy versus medical therapy alone in patients …
This NEJM editorial chronicles the invention, engineering foundation, and transformative clinical impact of optical coherence …
This multicenter, double-blind, randomized NOAH-AFNET 6 trial evaluated whether oral anticoagulation with edoxaban benefits patients …
A 21-year-old college student presented with progressive dyspnea, initially misdiagnosed as exercise-induced asthma. Diagnostic imaging …
This double blind, placebo controlled trial evaluated the cardiovascular efficacy of once daily oral semaglutide …
This editorial discusses the role of finerenone, a nonsteroidal mineralocorticoid receptor antagonist, in managing chronic …
Poor nutrition is a leading cause of preventable diseases, contributing to over half a million …
This large-scale population study assessed the prevalence and survival implications of actionable genotypes in 73 …
A 70 year old man with a history of hairy cell leukemia (in remission) and …
This editorial highlights the disparities in obesity management in primary care, particularly among socioeconomically disadvantaged …