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This population-based analysis from the Global Cardiovascular Risk Consortium pooled individual-level data from 1,518,028 participants …
This phase 3, double blind, placebo controlled trial evaluated the efficacy and safety of once …
This case report describes a 48 year old woman presenting with delusional thinking and transient …
This Perspective article advocates for expanding Medicaid coverage of comprehensive obesity-management interventions. The authors critique …
This case describes a 36-year-old woman who developed swelling and bluish discoloration of her left …
This NEJM Perspective by Richard Waring recounts his experience as a patient with atrial flutter …
This NEJM editorial assesses global data on five key modifiable cardiometabolic risk factors elevated systolic …
The ADVENT trial was a multicenter, randomized, single-blind, noninferiority study comparing pulsed field ablation (PFA) …
This review article examines the health effects of milk and dairy consumption, addressing both potential …
This NEJM Perspective explores ethical, regulatory, and clinical implications of implanting implantable cardioverter-defibrillators (ICDs) subject …
Evidence of the effectiveness of obesity treatment in underserved primary care populations is limited. This …
This case report describes an 80 year old woman with a history of progressive forehead …
This Clinical Decisions feature presents a case of a 67-year-old man with hypertension, obesity, and …
The ECLS-SHOCK trial investigated whether early extracorporeal life support (ECLS) improves survival in patients with …
: This NEJM editorial reviews the evolving evidence around complete revascularization in patients with STEMI …
The FIRE trial a multicenter, randomized study compared physiology-guided complete revascularization versus culprit-lesion-only PCI in …
This phase 3 randomized trial (APOLLO-B) assessed patisiran—a lipid nanoparticle siRNA therapeutic—in 360 patients with …
This clinical case study describes a 44 year old man presenting with fatigue, weight loss, …
This NEJM editorial interprets the ILUMIEN IV and OCTOBER trials, which evaluated whether optical coherence …
This NEJM case details a 75-year-old man with atrial tachyarrhythmias, tricuspid regurgitation, and pericarditis …
This correspondence presents three rare cases of spontaneous regression in ATTR amyloidosis–associated cardiomyopathy (ATTR-CM), a …
This clinical case study presents a 63 year old woman with a history of atraumatic …
This multicenter randomized controlled trial (NCT04415658) evaluated intravenous levothyroxine (30 µg/hr for ≥12 hr) versus …
This editorial interprets the findings of the ORBITA-2 trial—a double-blind, placebo-controlled study showing that …
This editorial highlights the efficacy of selpercatinib, a highly selective RET inhibitor, in treating RET-altered …
This NEJM correspondence describes a prospective study of 50 patients with severe aortic stenosis and …
This NEJM editorial assesses the CASTLE-HTx trial, which examined catheter ablation for atrial fibrillation in …
